Table 1.
Plasma ghrelin and IGF-I levels
| Group | Baseline ghrelin (ng/ml) | 6-h ghrelin (ng/ml) | 24-h ghrelin (ng/ml) | Baseline IGF-I (mg/ml) | 24-h IGF-I (mg/ml) | 13-d IGF-I (mg/ml) |
|---|---|---|---|---|---|---|
| Saline (n = 4) | 1.68 ± 0.13 | 2.22 ± 0.21 | 1.51 ± 0.13 | 1.24 ± 0.01 | 1.58 ± 0.25 | 0.96 ± 0.19 |
| Cisplatin (n = 4) | 1.50 ± 0.13 | 2.41 ± 0.25 | 2.1 ± 0.12a,b | 1.69 ± 0.15 | 1.09 ± 0.09a,b | 1.17 ± 0.1 |
| Cisplatin-ghrelin (n = 4) | 1.56 ± 0.2 | 2.59 ± 0.26a | 1.88 ± 0.24 | 1.59 ± 0.07 | 1.25 ± 0.21 | 1.31 ± 0.17 |
| Ghrelin (n = 4) | 1.49 ± 0.15 | 2.62 ± 0.33a | 2.09 ± 0.21b | 1.45 ± 0.22 | 1.54 ± 0.07 | 0.85 ± 0.08 |
a
P < 0.05 compared with same treatment group at baseline.
b
P < 0.05 compared with saline-treated animals.