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. 2007 Nov 15;149(2):580–586. doi: 10.1210/en.2007-1360

Figure 3.

Figure 3

Rescue of IGHD II mice A, Growth curves of wild-type (blue, n = 10), IGHD II (red, n = 8), 20R (yellow, n = 6), and 25R (green, n = 4) mice; B, pituitary dissections from 8-wk-old mice. The posterior pituitary is indicated within the dashed line (scale bar, 1 mm); C, fluorescent immunohistochemistry staining with anti-mGH on 20-μm pituitary sections taken from 10-wk-old mice. The posterior pituitary is indicated below the dashed line; D, serum IGF-I levels were measured by ELISA from 8- and 16-wk-old mice (n = 3 for each genotype). Wild-type, blue; IGHD II, red; 20R, yellow; 25R, green. Error bars are ±sem. From ANOVA for A and D, P < 0.0001. For complete statistical analyses, see supplemental Tables 3 and 4.