Fig. 5.
Effect of rhEPO on vWF-staining vascular structure in the ipsilateral hippocampus at 35 days after TBI. TBI (A, D) alone significantly increased the vascular density (stained brown, arrow as an example) in the DG. rhEPO (B, E) did not affect angiogenesis after TBI. The density of vWF-stained vasculature is shown in (G). Data represent mean ± SD. *P < 0.05 vs. Sham. N (mice/group) = 13 (male-saline), 12 (male-EPO), 8 (male-sham), 8 (female-saline), 8 (female-EPO), 7 (female-sham). Scale bar = 50μm.