Fig. 5.

Allergen sensitization model. (a) The mice were sensitized and challenged with ovalbumin as described in the protocol. There were three experimental groups, CycloOxygenase-2 TransActivated (COTA) with doxy, COTA without doxy and TA with doxy. (b) Prostaglandin E₂ (PGE₂) in bronchoalveolar lavage (BAL) fluid was also measured on day 16 from the mice of each group. (c) Total IgE level was measured in serum and (d) the cytokines was measured from lung homogenate on day 16 using a Bio-Plex system (Bio-Rad).