Table 3.

Multivariate analysis of the association between early-onset sepsis (EOS) and low mannose-binding lectin (MBL) levels and variant structural MBL2 genotypes, respectively.

	Possible EOS			EOS
Model	Adjusted OR	95% CI	P-value	Adjusted OR	P-value	95% CI
Model 1
Gestational age (1 week↑)	1·0	0·9–1·1	n.s.	1·0	0·8–1·2	n.s.
MBL plasma level
Normal (> 0·7 µg/ml)	Ref			Ref
Low (≤ 0·7 µg/ml)	1·7	0·6–4·6	n.s.	7·0	1·5–32·9	0·01
Model 2
Mode of delivery
Vaginal	Ref			Ref
Caesarean section	0·2	0·1–0·7	< 0·01	0·1	0·0–0·6	0·01
MBL plasma level
Normal (> 0·7 µg/ml)	Ref			Ref
Low (≤ 0·7 µg/ml)	1·8	0·6–4·9	n.s.	7·3	1·5–36·0	0·02
Model 3
Gestational age (1 week↑)	1·0	0·9–1·2	n.s.	1·0	0·8–1·2	n.s.
MBL2 genotype
Wild-type (YA/YA, YA/XA, XA/XA)	Ref			Ref
Variant (YA/O, XA/O, O/O)	3·3	0·8–13·2	n.s.	14·9	2·4–92·3	< 0·01
Model 4
Mode of delivery
Vaginal	Ref			Ref
Caesarean section	0·2	0·1–0·8	0·03	0·1	0·0–0·8	0·02
MBL2 genotype
Wild-type (YA/YA, YA/XA, XA/XA)	Ref			Ref
Variant (YA/O, XA/O, O/O)	3·1	0·7–13·0	n.s.	13·5	2·1–89·2	< 0·01

OR, odds ratio; CI, confidence interval; NS, not significant. Multinominal logistic regression was used.