Table 4.
Risks of infectious outcome during the first month of life.
| MBL plasma level | |||||
|---|---|---|---|---|---|
| Outcome measure | Normal (> 0·7 µg/ml) n | Low (≤ 0·7 µg/ml) n | OR | 95% CI | P-value |
| (a) According to mannose-binding lectin (MBL) plasma level (n = 88) | |||||
| Severe infection | 2 | 9 | 13·5 | 2·3–78·1 | < 0·01 |
| Culture-proven sepsis | 1 | 5 | 15·0 | 1·5–151·3 | 0·02 |
| Pneumonia | 1 | 4 | 12·0 | 1·1–126·1 | 0·04 |
| Suspected infection | 30 | 19 | 1·9 | 0·7–5·3 | n.s. |
| No infection | 21 | 7 | Ref | – | |
| MBL2 genotype | |||||
| Wild-type | Variant | ||||
| (b) According to MBL2 genotype (n = 70) | |||||
| Severe infection | 3 | 5 | 10·0 | 1·5–65·7 | 0·02 |
| Culture-proven sepsis | 1 | 2 | 12·0 | 0·8–177·4 | n.s. |
| Pneumonia | 2 | 3 | 9·0 | 1·0–78·6 | 0·05 |
| Suspected infection | 26 | 15 | 3·5 | 0·9–13·7 | n.s. |
| No infection | 18 | 3 | Ref | – | |
Multinominal logistic regression was used. The odds ratio (OR) can be interpreted as an estimation of the relative risk for the infectious outcome category compared to the ‘no infection’ category. CI, confidence interval; n.s., not significant.