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Deposition of opsonizing C3 split products on CD55- and/or CD46-deficient tumour cells (measured as common C3d moiety). Tumour cells were transfected with phosphorothioate oligonucleotides (S-ODNs), as indicated in the diagram. Following complement activation by polyclonal tumour-specific antibodies, deposited C3d molecules were quantified by flow cytometry. Data are shown from one representative experiment (of three).
