Table 2.

Genome-wide scan for loci linked with autoantibody production in (NZB × NZW)F₁ × NZB backcross mice

Trait	D7Nds5 to D7Mit145		D7Mit148 to D7Mit125		D16Mit5 to D16Mit6		H2z
	MLS	P value*	MLS	P value*	MLS	P value*	MLS	P value*
gp70 IC	2.0	0.0024	2.1	0.0018	0.70	—	0.03	—
IgG anti-dsDNA	1.9	0.0031	2.1	0.0018	0.20	—	2.4	8.8  ×  10−4
IgG anti-histone	1.3	0.014	1.4	0.011	0.10	—	4.4	6.7  ×  10−6
IgG anti-ssDNA	1.9	0.0031	2.1	0.0018	0.21	—	2.2	0.0015
IgG anti-chromatin	0.65	—	0.34	—	1.7	0.0051	3.2	1.2  ×  10−4
IgG1 anti-chromatin	0.11	—	0.05	—	1.6	0.0066	2.8	3.3  ×  10−4
IgG2a anti-chromatin	0.19	—	0.32	—	2.1	0.0018	2.8	3.3  ×  10−4
IgG3 anti-chromatin	1.2	0.019	0.50	—	0.89	—	0.21	—

^*, P values are shown for significant MLS at P < 0.02.