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The CB2R antagonist reverses CP55940-mediated inhibition of chemotaxis of microglia. Microglia were treated (1 h) with antagonist (10−6 M) or vehicle (VEH), treated (30 min) with CP55940 or vehicle and assessed (2 h) for migration against CM. *P<0.05, **P<0.01. n=3 per group. CB2R, CB2 receptor; CM, amoeba-conditioned medium.
