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. 2007 Oct 6;22(12):1695–1703. doi: 10.1007/s11606-007-0399-6

Table 5.

Association Between Intervention and Each After-Study Metabolic Condition

Metabolic Conditions: Intervention Group (n = 169) Control Group (n = 166) OR* 95% CI P
Before After Before After
Metabolic syndrome or hs-CRP ≥ 3 mg/L plus 2 components (%) 100 52.1 100 92.8 0.08 0.04–0.16 <.001
Metabolic syndrome (%) 70.4 34.9 72.3 65.7 0.28 0.18–0.44 <.001
Metabolic syndrome components(%)
 Central obesity 76.9 60.4 75.9 80.7 0.33 0.20–0.56 <.001
 Hypertension 94.1 84.6 93.4 89.2 0.67 0.35–1.29 .23
 Hyperglycemia 37.3 16.0 39.8 48.8 0.19 0.11–0.32 <.001
 Low HDL cholesterol 18.3 18.3 15.1 15.1 1.26 0.70–2.26 .43
 Hypertriglyceridemia 63.9 39.1 65.1 56.6 0.48 0.31–0.75 .001
Hs-CRP ≥ 3 mg/L (%) 56.2 34.9 50.6 66.3 0.26 0.16–0.41 <.001
Diabetes (%) 1.8 7.2 0.23 0.06–0.85 .03
Impaired fasting glucose (%) 37.3 14.2 39.8 41.6 0.22 0.13–0.39 <.001
Overweight (BMI ≥ 25 kg/m2) 91.7 83.4 85.5 89.8 0.58 0.30–1.10 .10
No. of components of the metabolic syndrome: OR‡ 95% CI P
 0–1 21.3 6.6
 2 29.6 43.8 27.7 27.7
 3 56.2 29.0 60.2 35.5 0.24 0.16–0.37 <.001
 ≥4 14.2 5.9 12.1 30.1

Hs-CRP= high-sensitivity C-reactive protein

*OR and 95% CI estimated through a multiple logistic regression model for each metabolic condition at the end of the study (intervention vs control group), adjusted for age, sex, and level of education.

The metabolic syndrome was defined in the presence of ≥3 of the following five criteria: fasting glucose ≥6.1 mmol/L; blood pressure ≥ 130/85 mmHg; triglycerides ≥1.69 mmol/L; HDL cholesterol <1.29 mmol/L (females) and <1.04 mmol/L (males); waist circumference >88 cm (females) and >102 cm (males) [8].

Ordinal logistic regression (score test for the proportional odds assumption: p = .20)