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. Author manuscript; available in PMC: 2008 Jan 30.
Published in final edited form as: Dev Biol. 2005 Jun 15;282(2):550–570. doi: 10.1016/j.ydbio.2005.04.010

Table 5.

Ventral expansion of gli2 expression domain in the forebrain of Hh pathway mutants

Gene Ventral margin of gli2 expression domain#
P
Wild-type* Mutant*
smub641 63 ± 8% (5s, 5e) 92 ± 8% (2s, 2e) < 0.02
dtrte370 63 ± 9% (4s, 4e) 74 ± 1% (7s, 5e) < 0.005
yotty119 68 ± 5% (6s, 5e) 83 ± 5% (5s, 5e) < 0.001
#

Forebrain sections were scored at the level of the epiphysis, which was identified by the presence of islet1-expressing cells (Figs. 8G–J). The dorsoventral height of the neural tube was measured, and the length of the gli2 expression domain (measured from the dorsal surface) was expressed as a fraction (%) of the height of the neural tube.

*

The first number in the parenthesis indicates the total number of sections scored, while the second number indicates the number of embryos these sections came from.