Fig. 6.

Scatter plot showing that molecular properties correlated with uptake in posterior glomeruli tend to be the same ones on both the medial and lateral aspects of the bulb. We determined the degree to which each of 13 molecular properties was correlated with average uptake in posterior modules on each aspect of the bulb, and then we plotted the correlation coefficient for the lateral module (h) relative to the correlation coefficient obtained for the medial module (H). Each point represents a single molecular property (1, log water solubility; 2, log vapor pressure; 3, hydrophilic-lipophilic balance; 4, percent hydrophilic surface; 5, hydrogen bond acceptor strength; 6, Hansen polarity; 7, hydrogen bond donor strength; 8, dipole moment; 9, number of freely rotatable bonds; 10, molecular length; 11, surface area; 12, molecular weight; 13, log P). The line is a result of least squares linear regression, the correlation coefficient for which was 0.82. Molecular properties related to water solubility and volatility were positively correlated with uptake in posterior modules both medially and laterally, while molecular properties related to size and hydrophobicity were negatively correlated with uptake in both aspects.