Table 3.
Summary of the mutations identified in essential genes as a result of this study.
| Gene | Description | Genomic Position (bp) | Chromosome | Mutant | Allele | Mutation | Protein Change | RNAi Phenotype | Mutagen |
| C16A3.3 | RRP5 Ribosomal RNA Processing Enzyme | 6383494..6389343 | III | let-716 | s2457 | G-A | 3rd Intron Splice Site | emb | EMS |
| s2626 | TGG-TGA | W1489 (opal) | |||||||
| fum-1 | Fumarase | 7465428..7467668 | III | let-768 | s2482 | TCG-TTG | S149L | emb | EMS |
| s2592 | CGT-CAT | R151H | |||||||
| s2628 | GGA-AGA | G88R | |||||||
| C29E4.8 | Adenylate Kinase | 7951844..7949909 | III | let-754 | s2622 | AAG-AAA | R150C | emb | EMS |
| aco-2 | Aconitase | 7973646..7977254 | III | let-722 | s2448 | GAA-AAA | E285K | emb | EMS |
| s2450 | GGG-GGA | G663D | |||||||
| s2588 | CGC-CGT | A687V |
emb = embryonic lethality
EMS = Ethylmethane Sulphonate