Figure 1.
Nifedipine block of K+ currents through ShBΔ6-46 T449V channels. (A) Current traces obtained from the inside-out patch in response to voltage steps from −100 mV to −20 mV, 0 mV, and +50 mV with (bottom) and without (top) nifedipine (50 μM) in the internal solution are shown. (B) Current amplitudes measured at the end of 200-ms pulses with (closed circles) and without (open circles) nifedipine (50 μM) in the internal solution.