Table 1.
Breeding strategy | Level of TF expression
|
Fatal mid-gestational hemorrhage (E12–E16) | Fatal post-partum hemorrhage | Placental blood pools | |
---|---|---|---|---|---|
Mother | Embryo | ||||
♂ −/−, h+ × ♀ −/−, h+ | Low | Low | 17/41 (42%) | 4/22 (18%) | Yes |
♂ +/+ × ♀ −/−, h+ | Low | Normal (+/−) | 0/43 | 6/43 (14%) | No |
♂ −/−, h+ × ♀ +/−, h+ | Normal (+/−) | Normal (+/−) | 0/273 | 0/273 | No |
Normal (+/−) | Low | Yes |
The breedings in the first row employed 6 male and 25 female mice. The breedings in the second row employed 5 male and 10 female mice. h+ represents h+/− or h+/+.