Table 3.
Histomorphometry-based parameters observed in sham-operated and ovariectomized mice
| Parameters | Mice | Mean | SD |
|---|---|---|---|
| BV/TV, % | Wild type: ovariectomized | 3.35* | 1.75 |
| Wild type: sham operated | 7.94 | 3.51 | |
| Osteopontin deficient: ovariectomized | 7.28 | 2.03 | |
| Osteopontin deficient: sham operated | 10.58 | 2.90 | |
| MAR, μm/day | Wild type: ovariectomized | 3.00 | 0.15 |
| Wild type: sham operated | 2.72 | 0.73 | |
| Osteopontin deficient: ovariectomized | 3.03 | 0.15 | |
| Osteopontin deficient: sham operated | 3.04 | 0.73 | |
| BFR/BV, μm3/μm2/day | Wild type: ovariectomized | 1042* | 388 |
| Wild type: sham operated | 600 | 284 | |
| Osteopontin deficient: ovariectomized | 774 | 165 | |
| Osteopontin deficient: sham operated | 606 | 260 |
BV/TV, bone volume/tissue volume; MAR, mineral apposition rate; BFR/BV, bone formation rate/bone volume; n = 4 in all cases.
*
Difference between the ovariectomized wild type and sham-operated wild type is statistically significant (P < 0.05).