Figure 3.

Translocation from the cytoplasmic to the membrane compartments of β₁ and β₂ cPKC isoforms and of σ₁ receptor in response to (+)pentazocine (100 nM). In basal conditions (Upper), β₁ and β₂ cPKC isoforms and σ₁ receptor immunofluorescence staining were found in the cytoplasm. A long perfusion of (+)pentazocine (Lower) produced a selective translocation of β₁ and β₂ cPKC isoforms and of the σ₁ receptor to the membrane vicinity. Neuronal images are single confocal sections. (Bars = 5 μm.)