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. 2007 Nov 19;8:36. doi: 10.1186/1745-6215-8-36

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Copyright © 2007 Pocock et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Changes in Movement Scores from Baseline to 3 Months and the Effects of 6 Months of Neurostimulation, as Compared with Sham Stimulation. As shown in Panel A, patients receiving effective high-frequency neurostimulation of the internal globus pallidus for 3 months had a significantly greater improvement in dystonic symptoms, as assessed by blinded ratings with the use of the Burke-Fahn-Marsden Dystonia Rating Scale, than did patients receiving sham stimulation. Each symbol denotes the change in scores from baseline to 3 months. The box plots represent the median and interquartile range. I bars show the range for each group. The changes in movement symptoms throughout the trial are shown for patients who were initially assigned either to the neurostimulation group (Panel B) or the sham-stimulation group (Panel C). (Kupsch et al. NEJM Nov 9, 2006 p1983)