Table 2.
Gene | GenBank | Name | Fold |
MFAP4 | NM_002404 | microfibrillar-associated protein 4 | 16.50 |
IL11RA | NM_004512 | interleukin 11 receptor, alpha | 5.90 |
RBP4 | NM_006744 | plasma retinol binding protein 4 | 37.38 |
AMPH | NM_001635 | amphiphysin | 8.27 |
INHBA | NM_002192 | inhibin, beta A (activin A, activin AB alpha polypeptide) | 6.94 |
C1QTNF3 | BC016021 | C1q and tumor necrosis factor related protein 3 | 20.25 |
PRELP | BC032498 | proline arginine-rich end leucine-rich repeat protein | 10.65 |
HDHD1A | NM_012080 | haloacid dehalogenase-like hydrolase domain containing 1A | -1.78 |
AGC1 | NM_013227 | aggrecan 1 (chondroitin sulfate proteoglycan 1) | 6.16 |
ANGPTL2 | NM_012098 | angiopoietin-like 2 | 6.67 |
C1orf24 | NM_052966 | chromosome 1 open reading frame 24 | 2.04 |
FMOD | NM_002023 | fibromodulin | 5.41 |
OLFM1 | NM_006334 | olfactomedin 1 | 2.55 |
FBLN1 | NM_006486 | fibulin 1 | 12.88 |
SSPN | NM_005086 | sarcospan | 4.40 |
CYFIP2 | BC026892 | cytoplasmic FMR1 interacting protein 2 | -2.68 |
MN1 | NM_002430 | meningioma 1 | 3.72 |
PTN | NM_002825 | pleiotrophin (osteoblast-specific factor 1) | 6.25 |
EGFR | NM_005228 | epidermal growth factor receptor | 2.71 |
TNN | NM_022093 | tenascin N | 6.67 |
ADCY2 | NM_020546 | adenylate cyclase 2 (brain) | 2.96 |
PDZRN3 | NM_015009 | PDZ domain containing RING finger 3 | 3.71 |
SPON1 | BC041974 | spondin 1, extracellular matrix protein | 4.73 |
APP | NM_000484 | amyloid beta (A4) precursor protein | 1.83 |
AUTS2 | NM_015570 | autism susceptibility candidate 2 | 1.94 |
GPC3 | NM_004484 | glypican 3 | 7.13 |
HAPLN1 | NM_001884 | hyaluronan and proteoglycan link protein 1 | 7.10 |
LHX6 | NM_014368 | LIM homeobox 6 | -1.80 |
Twenty-eight genes were identified as being significantly (false discovery rate adjusted P < 0.05) differentially expressed in unfused sutures compared to fused/fusing sutures. Genes are listed in order of significance with fold change relative to unfused sutures.