Table 6.
The overlap of the predicted domain interactions by APMM and LPM with those in iPfam, where λ denotes domain interaction probability, 'Single organism' means the training set of protein interactions is only from yeast, 'Multiple organisms' means the training set is from three organisms: yeast, worm and fly
Thresholds | Single organism (p-value) | Multiple Organisms (p-value) |
APMM | ||
λ >0.1 | 110 (8.1e-009) | 256 (8.4e-012) |
λ >0.2 | 99 (<1e-013) | 202 (2.9e-011) |
λ >0.3 | 61 (9.8e-010) | 149 (<1e-013) |
λ >0.4 | 52 (3.2e-010) | 127 (8.1-013) |
λ >0.5 | 49 (1.5e-013) | 91 (3.3e-012) |
LPM | ||
λ >0.1 | 109 (2.1e-008) | 256 (5.7e-013) |
λ >0.2 | 97 (8.8e-013 | 201 (5.9e-013) |
λ >0.3 | 61 (<1e-013) | 148(2.9e-012) |
λ >0.4 | 54 (4.4e-011) | 130 (<1e-013) |
λ >0.5 | 49 (<1e-013) | 93 (<1e-013) |