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. 2008 Feb;17(2):293–298. doi: 10.1110/ps.073237508

Figure 3.

Figure 3.

Number of polar contacts made by buried waters to protein and to other buried water molecules. Three contacts to protein are most common, but some waters make three polar contacts by interacting with other waters. Waters with more than three polar contacts to protein are relatively more abundant in TM proteins compared to WS proteins (cf. Williams et al. 1994).