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. 1999 May 1;113(5):601–620. doi: 10.1085/jgp.113.5.601

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Effects of inverse filtering on cAMP openings. Representative cAMP current traces at +80 mV are shown before (A) and after (B) inverse filtering along with amplitude histograms shown on log-linear axes. The dotted lines on the traces are separated by 2.2 pA. The amplitude histograms were fit by the sum of two Gaussians, which appear as parabolas on log-linear axes. The fit parameters before inverse filtering were: μ_open = 1.5 pA, σ_closed = 0.29 pA, σ_open = 0.65 pA, P _open = 0.006. The fit parameters after inverse filtering were μ_open = 2.1 pA, σ_closed = 0.49 pA, σ_open = 0.61 pA, P _open = 0.004.