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. 1999 Jan 1;113(1):111–124. doi: 10.1085/jgp.113.1.111

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A plot of mean open vs. mean shut time supports a second gating state at +40 mV. Mean open and mean shut times were calculated for each sweep used to generate Fig. 7 and plotted on a log–log scale. The plot for each voltage shows a main cluster of points that corresponds to the peak of the P _o-ex histogram in Fig. 7. However, a second cluster is observed in the plot of the data at +40 mV. The dashed line represents P _o = 0.5 and is presented to show the cutoff P _o used to calculate the fraction of sweep with high vs. low P _o gating.