TABLE 3.
Relative expression of the MfCYP51 and MfABC1 genes in M. fructicola field isolates
| Isolate | Relative growth (%)a | Propiconazole sensitivity phenotypeb | Relative expression ofc:
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MfCYP51
|
MfABC1
|
|||||||||
| Untreated
|
Propiconazole treated
|
Untreated
|
Propiconazole treated
|
|||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | |||
| Bmpc7 | 29.7 | R | 11.2 | 0.0 | 10.8 | 1.4 | 1.6 | 1.0 | 1.7 | 0.7 |
| Bmpc10 | 30.8 | R | 7.3 | 1.0 | 7.6 | 1.6 | 1.5 | 1.1 | 2.2 | 0.1 |
| Bmpc13 | 29.5 | R | 10.1 | 0.8 | 9.5 | 1.4 | 1.6 | 0.1 | 2.2 | 0.9 |
| GADL193 | 35.0 | R | 9.1 | 1.6 | 7.5 | 0.9 | 1.2 | 0.1 | 2.1 | 0.0 |
| GAAP5 | 36.3 | R | 10.3 | 1.5 | 10.0 | 0.7 | 0.6 | 0.3 | 1.9 | 0.9 |
| GAAP6 | 21.8 | R | 5.2 | 0.8 | 4.6 | 0.4 | 1.4 | 0.5 | 1.8 | 0.5 |
| GAAP12 | 0 | S | 1.9 | 0.5 | 1.3 | 0.3 | 2.6 | 0.7 | 1.5 | 0.0 |
| GADL3 | 0 | S | 3.4 | 0.2 | 1.9 | 0.4 | 2.8 | 0.3 | 1.1 | 0.6 |
| SCDL72 | 3.1 | S | 1.2 | 0.1 | 1.8 | 0.3 | 2.0 | 0.4 | 1.1 | 0.1 |
| SC99A3 | 5.0 | S | 2.3 | 1.0 | 1.8 | 0.0 | 1.0 | 0.0 | 1.6 | 0.9 |
| SC99A4 | 1.3 | S | 1.0 | 0.1 | 1.6 | 0.5 | 2.0 | 0.4 | 2.5 | 0.4 |
| Kac-18 | 0.4 | S | 1.0 | 0.2 | 0.9 | 0.4 | 2.2 | 0.1 | 2.5 | 0.4 |
Relative growth was calculated by expressing the growth of isolates on medium amended with 0.3 μg of propiconazole/ml as a percentage of the growth on nonamended medium.
An isolate was considered resistant (R) when the relative mycelial growth on medium amended with 0.3 μg of propiconazole/ml was ≥20%; all other isolates were considered sensitive (S).
The expression of the MfCYP51 or MfABC1 genes was normalized using the MfActin gene expression levels and then calibrated to the normalized MfCYP51 or MfABC1 mRNA value from the isolate with the lowest amount of MfCYP51 or MfABC1 mRNA. The mean and standard deviation values indicate the average relative expression between two independent biological experiments. Relative expression was determined in isolates subjected to water or 0.3 μg of propiconazole/ml 1 h before mRNA isolation.