TABLE 1.

MF in control and ENU-treated groups

Genotype	Control				ENU treatment
	Mouse	PFU (105)	No. of mutantsa	MF (10−5)	Mouse	PFU (105)	No. of mutants	MF (10−5)
p27+/+	1	3.61	13	3.6	1	3.63	159	43.8
	2	3.80	19	5.0	2	2.61	104	39.8
	3	2.88	15	5.2	3	3.91	203	51.9
	4	3.02	10	3.3	4	3.37	178	52.8
	5	2.88	11	3.8	5	2.62	167	63.6
	6	2.31	10	4.3	6	1.73	100	57.9
	7	3.25	15	4.6
	Mean ± SEM			4.3 ± 0.3				51.0 ± 3.3
p27+/−	1	5.68	23	4.1	1	4.36	253	58.1
	2	3.42	14	4.1	2	2.88	180	62.6
	3	2.72	14	5.1	3	4.35	253	58.2
	4	2.69	11	4.1	4	3.02	197	65.2
	5	3.01	8	2.7	5	3.55	250	70.5
	6	3.05	11	3.6	6	2.62	176	67.1
	7	3.45	10	2.9
	Mean ± SEM			3.8 ± 0.3				63.0 ± 2.0
p27−/−	1	2.04	19	4.4	1	1.88	223	118.3
	2	2.52	7	2.8	2	1.97	186	94.6
	3	1.21	3	2.5	3	2.13	255	119.9
	4	2.46	24	9.8	4	2.28	284	124.8
	5	2.08	9	4.3	5	2.57	321	124.9
	6	2.38	11	4.6
	7	2.20	13	5.9
	Mean ± SEM			5.1 ± 1.0				117.3 ± 4.7

^aThe number of mutants is corrected for potential clonal expansion.