FIG. 8.
A model for coordinated transcriptional activation of histone subtypes by cyclin E-Cdk2 substrate NPAT. SSRE, subtype-specific regulator element; SSBP, proteins, such as Oct-1 and HiNF-P that directly bind SSRE elements within the promoters of a histone subtype; TFs, transcription factors, P, phosphorylation. See text for details.