FIG. 2.

Spermiogenesis defect in B6129F1 nm1054 mice. (A and B) Sections of 8-week-old wild-type (A) and nm1054 (B) testes. Note the absence of mature sperm in the lumen of the nm1054 seminiferous tubule. Sections were stained with hematoxylin and eosin. Magnification, ×40. (C to E) Transmission electron microscopy of wild-type (C) and nm1054 (D and E) testes. Elongated dense bodies in panel D are nearly fully condensed sperm heads, but only occasional abortive tail structures can be identified in nm1054 testis sections (arrowheads in panels D and E).