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Heterochromatic localization of ICBP90 and Np95 depends on H3K9 methylation. (A) Immunostaining of Suv39h wild-type (left) and double-null (dn; right) MEFs with anti-trimethyl K9 H3 (green) and DAPI (blue). Representative interphase nuclei are shown. (B) Suv39h wild-type and double-null MEFs stained with anti-Np95 (green) and DAPI (blue). Np95 displays diffuse nuclear localization in Suv39h double-null fibroblasts.
