TABLE 6.
Adjusted RRs for immunological variables independently associated with malaria risk in the final model
| Immunological variable | Antibody level or no. of yr | Crude IRR (95% CI) | Adjusted IRR (95% CI) | P value from likelihood ratio test | (IRRadj − IRRcrude)/(1 − IRRcrude) (%) |
|---|---|---|---|---|---|
| IgG4 to GLURP | 0 | 1 | 1 | 0.0164 | |
| <Median | 0.36 (0.18-0.70) | 0.57 (0.32-1.02) | |||
| ≥Median | 0.37 (0.19-0.72) | 0.53 (0.30-0.92) | |||
| IgG3 to GLURP | Values transformed to log2 | 0.68 (0.58-0.80) | 0.87 (0.76-1.00) | 0.051 | |
| IgG1 to AMA1 | Values transformed to log2 | 0.75 (0.66-0.85) | 0.91 (0.82-1.01) | 0.092 | |
| Age | 0-3.5 | 1 | 1 | <0.001 | |
| 3.6-5.9 | 0.47 (0.30-0.74) | 0.60 (0.38-0.95) | 25 | ||
| 6.0-7.9 | 0.37 (0.23-0.59) | 0.48 (0.30-0.76) | 18 | ||
| 8.0-10.9 | 0.07 (0.04-0.14) | 0.10 (0.05-0.20) | 3.2 | ||
| 11.0-15 | 0.046 (0.02-0.10) | 0.07 (0.03-0.15) | 2.5 |