FIG. 4.
AO (A) and AHR (B) were assessed by whole-body plethysmography by measuring Penh in BALB/c mice inoculated with M. pneumoniae (Mp) or sterile SP4 broth (controls) and then treated with IL-12 or PBS-NMS. Values shown are means ± standard deviations (error bars). Data represent results from two separate experiments with four to eight mice in each group per time point. *, P = 0.048 between BALB/c mice inoculated with M. pneumoniae and treated with IL-12 or PBS-NMS, by two-way ANOVA; +, P < 0.001 between BALB/c mice inoculated with SP4 and treated with IL-12 or PBS-NMS (controls), by two-way ANOVA.