TABLE 4.
Genes showing at least twofold-altered mRNA levels in transcriptome comparisons of C. glutamicum WT(pVWEx1) with WTΔlldR(pVWEx1) and WTΔlldR(pVWEx1-lldR)
| Gene (identifier) | Annotation | mRNA level relative to WT(pVWEx1)
|
|
|---|---|---|---|
| WTΔlldR(pVWEx1)a | WTΔlldR(pVWEx1-lldR)b | ||
| NCgl2715 | Sulfate adenyltransferase subunit | 1.1 | 0.47 |
| NCgl2737 | Putative membrane protease subunit | 0.28 | 0.25 |
| NCgl2810 (ldhA) | LdhA, NAD+-dependent l-lactate dehydrogenase | 1.0 | 0.45 |
| NCgl2814 (lldR) | LldR, repressor of the NCgl2816-lldD operon | 0.15 | 24.9 |
| NCgl2816 | Transporter | 8.8 | 0.04 |
| NCgl2817 (lldD) | LldD, quinone-dependent l-lactate dehydrogenase | 6.8 | 0.09 |
a
The relative mRNA levels of strains WTΔlldR(pVWEx1) and WT(pVWEx1) were compared during exponential growth on minimal medium containing 100 mM ribose.
b
The relative mRNA levels of strains WTΔlldR(pVWEx1-lldR) and WT(pVWEx1) were compared during exponential growth on minimal medium containing 50 mM fructose plus 100 mM l-lactate.