FIG. 8.

Histopathological observations in muscles of mice infected for 2 months with the virulent T. cruzi Tulahuen strain. The animals had been primed 14 months before the Tulahuen infection, with either WT, L16, or saline (see the text). Each dot represents a mouse. Note the significant degree of protection against necrosis and calcium deposits (P = 0.018) (left panel) or lymphomonocytic infiltrates (P = 0.0085) (right panel) bestowed by previous L16 infection, but not by WT infection. −, absent; +, slight; ++, moderate; +++, severe.