FIG. 3.

Number of differentially expressed B. burgdorferi ORFs grouped by putative protein functions. ORFs (n = 72) included in this graph passed three statistical tests, SAM, partek, and t tests, and were up- or down-regulated at least twofold. The graph displays the number of differentially expressed B. burgdorferi genes, grouped by putative protein function as assigned by TIGR as COGs, after infection of H4 neuroglial cells. Gray bars represent the number of up-regulated genes, and the black bars represent the number of down-regulated genes.