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. 2007 Nov 21;15(1):71–75. doi: 10.1128/CVI.00321-07

TABLE 1.

AVA vaccination histories of the human subjects and LF-to-EF ratios of antibody responses and neutralization titers

Sample Total no. of inoculations No. of mos since last inoculation Antibody response ratio, LF/EFa Neutralization ratio, LF/EFb
S1 6 30 0.7 2.0
S2 6 16 0.6 1.0
S3 5 12 2.3 0.5
S4 5 12 0.3 2.0
S5 4 6 0.3 1.0
S6 5 9 11.8 1.0
S7 5 1 3.6 1.0
S8 5 12 1.3 0.5
Pool 0 NAc NRd NA
a

Serum sample reactivity to PA, LF, or EF proteins was detected by Western blotting. Band intensity was quantified, and the ratio of LF antibody response to EF antibody response was calculated.

b

Ratio of titers determined by comparing antibody-mediated neutralization of LF-induced lysis to neutralization of EF-induced cAMP increases.

c

NA, not applicable.

d

NR, not reactive.