TABLE 4.
Overview of TLR expression
| Cell type | Expression ofa:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| TLR1 | TLR2 | TLR3 | TLR4 | TLR5 | TLR6 | TLR7 | TLR8 | TLR9 | TLR10 | |
| Resting HMEC-1 | ++ | + | + | +++ | + | + | − | − | + | + |
| Activated HMEC-1 | → | ↑ | ↑ | → | → | ↓ | ↑ | → | → | → |
| Resting HDMEC | + | +++ | + | +++ | + | + | − | − | + | − |
| Activated HDMEC | ↑ | ↑ | ↑ | → | ↓ | → | ↑ | ↑ | → | ↑ |
a
+, weak TLR expression (100 ng of cDNA needed for a detection signal); ++, medium-strength TLR expression (20 ng of cDNA needed for medium-sized CT values); +++, strong TLR expression (4 ng of cDNA needed for medium-sized CT values); −, no TLR expression within 40 cycles; ↑, increase of TLR expression; ↓, decrease of TLR expression; →, no significant changes in TLR expression.