TABLE 3.
BUN levels and blood creatinine levels (means ± standard errors) for groups of mice infected with A. fumigatus and treated three times with the indicated doses of D5W, Anfo, or AmBi
Measurement | Treatment group | Level (mg/dl) in samples from mice receiving 3 doses of:
|
||||
---|---|---|---|---|---|---|
D5W | 3 mg/kg | 5 mg/kg | 7.5 mg/kg | 15 mg/kg | ||
BUN | Control (D5W) | 12.80 ± 1.50 | ||||
Anfo | 14.00 ± 1.30 | 22.20 ± 6.73 | 78.20a ± 8.09 | |||
AmBi | 12.60 ± 0.81 | 13.60 ± 1.03 | 12.00 ± 0.45 | 17.20 ± 0.92 | ||
Creatinine | Control (D5W) | 0.34 ± 0.02 | ||||
Anfo | 0.36 ± 0.02 | 0.42 ± 0.02 | 0.64a ± 0.05 | |||
AmBi | 0.34 ± 0.02 | 0.38 ± 0.02 | 0.36 ± 0.02 | 0.38 ± 0.02 |
P = 0.008 versus D5W; Mann-Whitney test.