TABLE 3.
MICs of time-kill study strains tested by broth macrodilution
Drugj | MIC (μg/ml) for HMC strain:
|
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
1072a,e,i | 63a,d,h | 1074a,d,i | 5055a,f,h | 100b,d,h | 99b,d,h | 441b,e,h | 5048b,f,h | 1058c,d,i | 228c,e,h | 3583c,f,h | 1541c,g,i | |
DC-159a | 1 | 0.12 | 1 | 0.12 | 0.12 | 0.12 | 0.12 | 0.12 | 0.5 | 0.12 | 0.12 | 1 |
LEVO | 16 | 1 | 16 | 1 | 1 | 1 | 0.5 | 1 | 8 | 1 | 1 | 16 |
MOXI | 4 | 0.25 | 4 | 0.25 | 0.25 | 0.12 | 0.12 | 0.12 | 2 | 0.12 | 0.12 | 4 |
GATI | 8 | 0.5 | 4 | 0.25 | 0.5 | 0.25 | 0.25 | 0.25 | 4 | 0.5 | 0.25 | 4 |
GEMI | 0.5 | 0.06 | 0.25 | 0.03 | 0.06 | 0.06 | 0.016 | 0.03 | 0.12 | 0.06 | 0.03 | 0.5 |
Amox/Clav | 0.016 | 0.016 | 0.03 | 0.03 | 0.25 | 0.25 | 0.12 | 0.5 | 2 | 2 | 2 | 4 |
Azithro | >64 | 0.016 | 0.03 | 2 | 0.03 | 0.016 | >64 | 4 | 0.06 | >64 | 2 | >64 |
Penicillin susceptible.
Penicillin intermediate.
Penicillin resistant.
Macrolide susceptible.
ermB positive.
mefA positive.
L4 mutations.
Quinolone susceptible.
Quinolone resistant.
LEVO, levofloxacin; MOXI, moxifloxacin; GATI, gatifloxacin; GEMI, gemifloxacin; Amox/Clav, amoxicillin-clavulanic acid; Azithro, azithromycin.