TABLE 1.
Parameter | Mean (SD) |
---|---|
Cmax (μg/ml) | 116 (30) |
Tmax (h) | 1.00 (0) |
AUC0-24 (μg·h/ml) | 785 (111) |
t1/2 (h) | 7.41 (1.08) |
CLss (ml/h/kg) | 13.0 (1.9) |
MRT (h) | 9.42 (1.54) |
Vdss (ml/kg) | 122 (22) |
Cmin (μg/ml) | 8.11 (2.28) |
CLss, clearance at steady state; MRT, mean residence time; Tmax, time to Cmax; Vdss, volume of distribution at steady state.