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Effect of disruption of host cell actin alone on parasite egress. HFFs were pretreated either with 3 μM mycalolide B or with DMEM solvent (control) for 10 min before parasites were allowed to invade. Percent egress is the percentage of lysed vacuoles at 48 h or 72 h postinvasion relative to the level at 30 h postinvasion. Data are means from three independent experiments. Each error bar equals 1 standard deviation.
