FIG. 4.
Activity of daptomycin with or without rifampin at 300 mg every 8 h (q8h) against breakthrough isolate SA0629 and daptomycin-nonsusceptible isolate SA0701 in an in vitro pharmacodynamic model over 96 h in duplicate. D6, daptomycin in 6-mg/kg doses given q24h; R, rifampin at 300-mg doses given q8h; GC, growth control. MICs are in μg/ml.