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In vitro epitope processing and presentation of HBV multiepitope DNA vaccine in human cells
| HLA restriction | Epitope | Level identified by mass spectrometry (fmol) | Copies/cella |
|---|---|---|---|
| A2 | pol 538 | 15 | 75 |
| pol 562 | |||
| pol 455 | 250 | 1,250 | |
| core 18 | 6 | 30 | |
| env 183 | 3 | 15 | |
| env 335 | |||
| B7 | env 313 | 50 | 250 |
| core 19 | 75 | 350 | |
| pol 354 | 400 | 2,000 | |
| pol 429 | 700 | 3,500 | |
| pol 640 | 5 | 25 | |
| pol 530 |
Copies/cell is the approximate number of copies of the peptides per cell, calculated using the starting cell number.
