TABLE 5.
Additional epitopes present in INX 102-3697
|
Epitope in construct
|
Additional HLA binding epitope
|
Reference | ||||
|---|---|---|---|---|---|---|
| Name | HLA type | Sequence | HLA type | Sequence | Immunogenicity type | |
| pol 14 | A3 | HTLWKAGILYK | A3 | TLWKAGILYK | Human acute HBV infection | 4 |
| env 249 | A1 | ILLLCLIFLL | A2 | ILLLCLIFLL | 46 | |
| A2 | LLLCLIFLL | Human acute HBV infection | 46 | |||
| A2 | ILLLCLIFL | Human acute HBV infection | 46 | |||
| pol 530 | B7 | FPHCLAFSYM | B7 | FPHCLAFSY | 50 | |
| pol 767 | DR | AANWILRGTSFVYVP | A2 | ILRGTSFVYV | Human acute HBV infection | 39 |
| env 332 | A24 | RFSWLSLLVPF | A24 | SWLSLLVPF | Human acute HBV infection | 22 |
| pol 415 | A1 | LSLDVSAAFY | A11 | LSLDVSAAFY | HLA transgenic mice | 1 |