FIG. 4.
Akt inhibitor inhibited growth of PIV5, MuV, and MeV. MDBK (a) or HeLa (b) cells were infected with PIV5 at a MOI of 5 and treated with DMSO or Akt inhibitor (0.5 μM AktIV inhibitor or 10 μM Akt 1/2 inhibitor). The media from the cells were collected at the indicated times postinfection. (c) Inhibition of MuV growth. HeLa cells were infected with MuV at a MOI of 3 and treated with DMSO or AktIV inhibitor (0.5 μM). (d) Inhibition of MeV growth. Vero cells were infected with MeV at a MOI of 3 and treated with DMSO or AktIV inhibitor (2 μM). For all samples, virus titers were determined by plaque assay.