FIG. 4.

Single-cycle multiplication of vaccinia virus mutants lacking the N- and C-terminal domains of E3L in PKR⁺, PKR^kd, and PKR^kd-con cells. Cells were infected at an MOI of 5 with either WT, ΔE3L, Δ26C, or Δ83N virus. At 24 h p.i., cells were harvested and virus yields were determined by plaque titration on RK₁₃ cells. The results shown are the means ± standard deviations determined from a minimum of three experiments.