FIG. 6.

Antibody profiling of macaques inoculated with MVA or Dryvax shows both profiles are dominated by antibodies to structural proteins. Antibody profiles of cynomolgus macaques pre- and postimmunization with MVA/MVA (n = 6) (A), MVA/DVX (n = 6) (B), or −/DVX (n = 6) (C) according to the schedules shown in Fig. 1B. Note that week 14 of the Dryvax-alone experiment (C) corresponds to week 6 postvaccination (Fig. 1B). Data representation is as described for Fig. 4. (D) Virion proteins determined by mass spectroscopy studies of WR virions are indicated by the filled cells; data in columns a to c are from references 8, 28, and 38, respectively.