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Neutralization competition with V1 and V3 derived peptides. V1 and V3 peptides derived from SF162 Env were used to block the activities of neutralizing antibodies in sera from macaques immunized with SF162gp140 (12). The percent reduction in serum neutralizing activity in the presence of the V1 or V3 peptide was determined at the concentration resulting in 80% inhibition of infection, as discussed in Materials and Methods.
