TABLE 4.
Organization and analysis of partial lactonamycin Z gene cluster from S. sanglieri AK 623
| Gene designation | Size (aa)a | Protein homolog(s) [GenBank accession number(s)], % similarity/% identity | Possible function, % identity to S. rishiriensis homolog |
|---|---|---|---|
| lcz24 | 93 | Sim4 (AAL15582), 71/52 | Acyl carrier protein, 81 |
| lcz25 | 335 | TcmN (P16599), 66/49 | O-Methyltransferase, 83 |
| lcz26 | 83 | RPC_2301 (ABD87855), 70/44 | Acyl carrier protein, 69 |
| lcz27 | 153 | RubF (AAG03070), 70/58 | Polyketide cyclase, 87 |
| lcz28 | 524 | SAV1250 (BAC68960), 63/51 | Carboxylic acid adenylation, 75 |
| lcz29 | 109 | ElmI (AAF73052), 64/46 | Polyketide cyclase, 83 |
| lcz30 | 145 | TcmJ (P16558), 70/50 | Polyketide cyclase, 90 |
| lcz31 | 421 | TcmK (P16538), 80/67 | KSα, 90 |
| lcz32 | 406 | TcmL (P16539), 74/65 | KSβ, 87 |
| lcz33 | 115 | TcmH (P39889), 67/52; ElmH (AAF73051), 64/43 | Monooxygenase, 80 |
| lcz34 | 246 | G111934 (BAC89875), 52/37 | Thioesterase, 70 |
| lcz35 | 323 | TcmO (P39896), 62/49 | O-Methyltransferase, 84 |
| lcz36 | 427 | UrdGT1a (AAF00214), 66/51 | Glycosyltransferase, 83 |
| lcz37 | 137 | SAV3997 (BAC71709), 50/34 | Hypothetical protein, ester cyclase, 81 |
| lcz38 | 491 | SAV1847 (BAC69558), 65/47 | Membrane efflux protein, 81 |
a
aa, amino acids.