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HPLC chromatograms of extracts of clone A replicon cells incubated for 48 h with PSI-6130 in the absence of zebularine (top panel) and in the presence of 10 μM (middle panel) and 50 μM (bottom panel) zebularine. Peaks were identified from the chromatograms of the standards. The PSI-6130-MP and RO2433-MP peaks were close to the background levels, with retention times of 8.57 min and 11.83 min, respectively.
