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Strains used in this study and their MLSB phenotypes
| Strain | Characteristic | MIC (μg/ml)a
|
CLI D-testb | ||
|---|---|---|---|---|---|
| ERY | CLI | iCLI | |||
| AP200 | Clinical isolate, donor | 1 | 0.06 | 64 | iR |
| FP11 | Recipient | 0.023 | 0.015 | ND | S |
| TP1 | Transformant | 1 | 0.015 | 32 | iR |
| RM5 | TP1 Δerm(TR) | 0.023 | 0.015 | ND | S |
ERY, erythromycin; CLI, clindamycin; iCLI, clindamycin after induction with 0.05 μg/ml erythromycin; ND, not done.
CLI D-test, clindamycin double-disk test; iR, inducible resistance; S, susceptible.
