TABLE 3.
Homologies of the ORFs present in a ∼10-kb region including erm(TR) in S. pneumoniae AP200
| ORF | Homologous protein (microorganism; GenBank accession no.)a | Amino acid identity (%)b | Amino acid similarity (%)b |
|---|---|---|---|
| orf1 | Hypothetical protein (S. pyogenes MGAS10750; ABF38649) | 96/101 (95%) | 98/101 (97%) |
| Putative conjugative transposon protein (C. difficile 630; CAJ68737) | 67/102 (65%) | 84/102 (82%) | |
| orf2 | Transcriptional regulator TetR family (S. pyogenes MGAS10750; ABF38650) | 209/210 (99%) | 210/210 (100%) |
| Transcriptional regulator TetR family (D. hafniense; EAT51867) | 91/209 (43%) | 142/209 (67%) | |
| orf3 | Tetronasin resistance ATP-binding protein (S. pyogenes MGAS10750; ABF38651) | 293/293 (100%) | |
| ABC transporter ATP-binding protein (O. iheyensis; BAC12676) | 251/292 (85%) | 274/292 (93%) | |
| ABC transporter ATP-binding protein (E. faecium; CAL36556) | 250/292 (85%) | 268/292 (91%) | |
| orf4 | Tetronasin resistance transmembrane protein (S. pyogenes MGAS10750; ABF38652) | 567/568 (99%) | 568/568 (100%) |
| Putative ABC-2 type transport system permease protein (E. faecium; EAN08886) | 305/536 (56%) | 424/536 (79%) | |
| orf5 | erm(TR) (S. pyogenes; AAB60941) | 243/243 (100%) | |
| erm(TR) (S. pyogenes MGAS10750; AAB60941) | 243/243 (100%) | ||
| erm(A) (S. aureus; BAB42746) | 197/242 (81%) | 218/242 (90%) | |
| orf6 | Spectinomycin phosphotransferase (S. pyogenes MGAS10750; ABF38655) | 173/174 (99%) | 174/174 (100%) |
| Spectinomycin phosphotransferase (L. pneumophila Lens; CAH15775) | 45/143 (31%) | 73/143 (51%) | |
| orf7 | Cytidine deaminase (S. pyogenes MGAS10750; ABF38656) | 28/28 (100%) | |
| orf8 | DNA recombinase (B.cereus ATCC 10987; AAS39355) | 36/48 (75%) | 40/48 (83%) |
| orf9 | Hypothetical protein CbeiDRAFT_2337 (C. beijerincki; EAP59839) | 62/141 (43%) | 86/141 (60%) |
| Putative transposase (E. faecalis; AAF70552) | 44/141 (31%) | 73/141 (51%) | |
| orf10 | Transposase IS116/IS110/IS902 family protein (T. vaginalis; EAX95005) | 105/110 (95%) | 108/110 (98%) |
| Putative transposase (E. faecalis, AAF70552) | 42/108 (38%) | 63/108 (58%) | |
| Transposase IS116/IS110/IS902 (S. suis; EAP39924) | 37/91 (40%) | 56/91 (61%) | |
| orf11 | Relaxase (S. pyogenes MGAS10750; ABF38658) | 329/332 (99%) | 331/332 (99%) |
| Putative conjugative transposon mobilization protein (C. difficile 630; CAJ68743) | 296/443 (66%) | 353/443 (79%) | |
| Relaxase (S. pyogenes MGAS10750; ABF38660) | 109/112 (97%) | 111/112 (99%) | |
| orf12 | Hypothetical protein (S. pyogenes MGAS10750; ABF38661) | 106/118 (89%) | 113/118 (95%) |
| Putative conjugative transposon mobilization protein (C. difficile 630; CAJ68744) | 85/118 (72%) | 100/118 (84%) |
a
D. hafniense, Desulphitobacterim hafniense; O. iheyensis, Oceanobacillus iheyensis; E. faecium, Enterococcus faecium; C. beijerincki, Clostridium beijerincki; S. suis, Streptococcus suis.
b
Values are the ratios of the number of identical or similar amino acids, as indicated, to the total number of amino acids in the region of similarity.